CLINICAL SIGNIFICANCE
Calcium is the most abundant and one of the most important minerals in the human body. Approximately 99% of body calcium is found in bones. A decrease in albumin level causes a decrease in serum calcium. Low levels of calcium are found in hypoparathyroidism, pseudohypoparathyroidism, vitamin D deficiency, malnutrition and intestinal malabsortion. Among causes of hypercalcemia are cancers, large intake of vitamin D, enhaced renal retention, osteoporosis, sarcosidosis, thyrotoxicosis, hyperparathyroidism.
Clinical diagnosis should not be made on a single test result; it should integrate clinical and other laboratory data.
REAGENTS
R
Arsenazo
III |
Imidazol Buffer pH
6.5
Arsenazo III |
100
mmol/L
120
mmol/L |
CALCIUM CAL Calcium aqueous primary standard 10 mg/dL |
REFERENCE VALUES
- Serum or plasma:
+ Adults 8.5-10.5 mg /dL 2.1-2.6 mmol/L
+ Children 10 -12 mg/dL 2.5 - 3 mmol/L
+ Newborns 8 -13 mg/dL 2 -
3.25 mmol/L
- Urine:
+ Adults 50 - 300 mg/24h 1.25 - 7.5 mmol/24h
+ Children 80 -160
mg/24h 2 - 4 mmol/24h
These values are for orientation purpose; each laboratory should establish its own reference range.
PACKAGING
- Ref: 1001065 - 3 x 50 mL